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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1A
All Species:
7.58
Human Site:
S183
Identified Species:
18.52
UniProt:
Q02539
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02539
NP_005316.1
215
21842
S183
K
P
K
K
V
A
K
S
P
A
K
A
K
A
V
Chimpanzee
Pan troglodytes
XP_527252
215
21792
S183
K
P
K
K
V
A
K
S
P
A
K
A
K
A
V
Rhesus Macaque
Macaca mulatta
P40286
208
22075
S182
K
G
K
Q
Q
Q
K
S
P
V
K
A
R
A
T
Dog
Lupus familis
XP_545380
215
21790
P183
A
K
K
V
A
K
S
P
A
K
A
K
A
V
K
Cat
Felis silvestris
Mouse
Mus musculus
P43276
223
22558
P180
K
A
K
A
A
A
K
P
K
K
A
A
K
S
P
Rat
Rattus norvegicus
P15865
219
21969
K180
P
K
K
A
K
A
T
K
A
K
K
A
P
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
K180
T
K
S
P
R
K
T
K
T
A
K
P
K
R
A
Chicken
Gallus gallus
P08284
219
22026
P181
K
A
A
K
A
G
R
P
K
K
A
A
K
S
P
Frog
Xenopus laevis
P06892
210
21355
V184
K
T
A
V
K
P
K
V
A
A
K
S
P
A
K
Zebra Danio
Brachydanio rerio
XP_002667660
183
19011
P157
A
K
K
A
T
K
S
P
K
K
A
K
V
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
51.6
82.3
N.A.
68.6
70.7
N.A.
68.6
64.8
53.9
54.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
64.1
87.4
N.A.
73.5
77.1
N.A.
78
72.5
64.6
64.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
6.6
N.A.
40
26.6
N.A.
20
26.6
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
66.6
6.6
N.A.
46.6
26.6
N.A.
20
40
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
20
30
30
40
0
0
30
40
40
60
10
50
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
60
40
70
30
20
30
50
20
30
50
60
20
50
10
30
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
20
0
10
0
10
0
40
30
0
0
10
20
0
20
% P
% Gln:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
10
0
0
0
0
0
10
10
0
% R
% Ser:
0
0
10
0
0
0
20
30
0
0
0
10
0
20
10
% S
% Thr:
10
10
0
0
10
0
20
0
10
0
0
0
0
0
10
% T
% Val:
0
0
0
20
20
0
0
10
0
10
0
0
10
10
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _